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CAS Number: 145414-76-2
Cdc-2 and retinoblastoma are strongly inhibited
CAS Number: 1219409-06-9
Chemical Name: 5-fluoro-2-{[1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile
Molecular Weight: 4230
ADX 10059 hydrochloride Size:Contact [email protected] for quotation CAS Number: 145414-76-2ADX 10059 hydrochloride is a potent and selective negative allosteric modulator of mGlu5 receptor with IC50 value of 17. 1 nM . Metabotropic glutamate receptor 5 (mGlu5 receptor) is a G protein coupled receptor and is a receptor for glutamate, which is a primary neurotransmitter involved in signaling in the central nervous system . ADX 10059 hydrochloride is a potent and selective mGlu5 receptor negative allosteric modulator. In patients with
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